The Single Best Strategy To Use For ceesdekker.net
The Single Best Strategy To Use For ceesdekker.net
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Employing single-molecule optical and AFM imaging and force-spectroscopy approaches, we search for to unravel the mechanistic facets of the structure and dynamics of chromosomes. Our investigate passions contain:
Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transport of macromolecules
To be a human being, I provide the biblical assignment to explore and use every little thing in development for the good thing about my neighbour. I do not knowledge any conflict involving religion and science. Quite the opposite, my faith stimulates me to complete science, to get open up-minded on the globe.’
Nanofabrication of electrodes with sub-five nm spacing for transportation experiments on solitary molecules and metallic clusters
We create point-of-treatment diagnostics examination of neglected tropical ailments within useful resource-minimal settings, based on Crspr/Cas9 detecting of pathogen’s DNA in system fluids.
Instance (three) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is proven in gray, the rim in the pore is highlighted in red, and also a 3D rendering in the motion with the DNA rod is shown.
Since 2000 he moved to one-molecule biophysics and nanobiology, with investigation from DNA supercoiling scientific studies of nucleosomes and DNA restore proteins to DNA translocation through nanopores. A short while ago his exploration has focused on learning mobile division with microorganisms on chip, whilst his ultimate fascination is inside the direction of noticing synthetic cells.
He also located time to jot down numerous guides, deliver Just about forty thousand tweets and lead An effective investigate group at Delft University of Technological know-how. ‘It doesn’t truly feel like do the job’, he claims. ‘I’m just terribly curious.’
Being familiar with essential procedures regulating the spatial and dynamic organisation of your DNA in Are living cells.
At the moment, we also realized that it should be possible to use only one semiconducting carbon nanotube to help make a transistor — and we established out to make it. We stretched personal semiconducting nanotubes across metallic electrodes and used the fundamental silicon substrate for a gate electrode, developing The fundamental three-terminal structure of the discipline-impact transistor (Fig.
Illustration (4) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is revealed in gray, the rim on the pore is highlighted in crimson, along with a 3D rendering on the motion of your DNA rod is shown.
Cees Dekker is Distinguished College Professor at TU Delft. Properly trained to be a physicist, he pioneered nanotechnology with lots of discoveries on carbon nanotubes during the nineteen nineties. Considering the fact that 2000, he moved to one-molecule biophysics and nanobiology. His latest exploration concentrates on (i) nanopores for protein sequencing; (ii) chromosome framework, particularly SMC motor protein; and (iii) building a living artificial mobile from lifeless molecules. Dekker is undoubtedly an elected member on the KNAW and fellow on the APS along with the IOP.
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It was an incredibly attention-grabbing time, in the course of which I gained a lot of help from Delft College of Technological know-how, exactly where I used to ceesdekker.net be a professor at enough time, And that i started numerous collaborations with molecular biologists. That aided me master a great deal.’